Work

Elimination of depth degeneracy in optical frequency-domain imaging through polarization-based optical demodulation

Year: 2006

Type: article

Abstract: A novel optical frequency-domain imaging system is demonstrated that employs a passive optical demodulation circuit and a chirped digital acquisition clock derived from a voltage-controlled oscillator. The demodulation circuit allows the separation of signals from positive and negative depths to better than 50 dB, thereby eliminating depth degeneracy and doubling the imaging depth range. Our system design is compatible with dual-balanced and polarization-diverse detection, important techniques in the practical biomedical application of optical frequency-domain imaging.

Source: Optics Letters

DOI: 10.1364/ol.31.000362

Authors: B. J. Vakoc, S. H. Yun, G. J. Tearney, B. E. Bouma

Institutions: Harvard University, Massachusetts General Hospital

Language: English

Topic: Optical Coherence Tomography Applications

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

Open Access status: green

Funders: National Heart, Lung, and Blood Institute, National Cancer Institute

Awards: G1545476000, G1990521654, G3977717423, Natural History of Vulnerable Coronary Plaques, G941165375