Work

Specific methionine oxidation of cytochrome c in complexes with zwitterionic lipids by hydrogen peroxide: potential implications for apoptosis

Year: 2014

Type: article

Abstract: concentrations to the submillimolar levels registered during initiation of the apoptotic program may represent one signaling event that triggers the gain in peroxidatic function of the Cyt-c molecules bound to the abundant PE and PC membrane components. As the activated protein is a chemically stable species, it can potentially bind and oxidize important targets, such as CL.

Source: Chemical Science

DOI: 10.1039/c4sc02181a

Authors: Daiana A. Capdevila, Waldemar A. Marmisollé, Florencia Tomasina, Verónica Demicheli, Magdalena Portela, Rafael Radi, Daniel H. Murgida

Institutions: Consejo Nacional de Investigaciones Científicas y Técnicas, Universidad de Buenos Aires, Instituto de Química-Física de los Materiales, Medio Ambiente y Energía, Universidad de la República de Uruguay, Institut Pasteur de Montevideo

Language: English

Topic: Cell death mechanisms and regulation

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funders: Agencia Nacional de Investigación e Innovación, Consejo Nacional de Investigaciones Científicas y Técnicas, Universidad de la República Uruguay, Agencia Nacional de Promoción Científica y Tecnológica, Secretaría de Ciencia y Técnica, Universidad de Buenos Aires

Awards: G3958464607, G5118346162, G7378882120, G7696816827, G841842749, G8559644500

OpenAlex ID: W2082043809

FWCI: 1.778

Cites: 64

Cited by: 63

Related to: 10