Work

Conducting polymer functionalized single-walled carbon nanotube based chemiresistive biosensor for the detection of human cardiac myoglobin

Year: 2014

Type: article

Abstract: We report the fabrication of a single-walled carbon nanotube (SWNT) based ultrasensitive label-free chemiresistive biosensor for the detection of human cardiac biomarker, myoglobin (Ag-cMb). Poly(pyrrole-co-pyrrolepropylic acid) with pendant carboxyl groups was electrochemically deposited on electrophoretically aligned SWNT channel, as a conducting linker, for biomolecular immobilization of highly specific cardiac myoglobin antibody. The device was characterized by scanning electron microscopy, source-drain current-voltage (I-V), and charge-transfer characteristic studies. The device exhibited a linear response with a change in conductance in SWNT channel towards the target, Ag-cMb, over the concentration range of 1.0 to 1000 ng ml−1 with a sensitivity of ∼118% per decade with high specificity.

Source: Applied Physics Letters

DOI: 10.1063/1.4897972

Authors: Nidhi Puri, Asad Niazi, Ashok M. Biradar, Ashok Mulchandani, Rajesh

Institutions: Jamia Millia Islamia, Council of Scientific and Industrial Research, CSIR National Physical Laboratory of India, University of California, Riverside

Language: English

Topic: Electrochemical sensors and biosensors

Subfield: Electrical and Electronic Engineering

Field: Engineering

Domain: Physical Sciences

Open Access status: green

Funders: Council for Scientific and Industrial Research, South Africa, National Physical Laboratory

OpenAlex ID: W2082936496