Work

The protein tyrosine phosphatase, Shp2, positively contributes to FLT3-ITD-induced hematopoietic progenitor hyperproliferation and malignant disease in vivo

Year: 2012

Type: article

Source: Leukemia

DOI: 10.1038/leu.2012.308

Authors: S C Nabinger, X J Li, B Ramdas, Y He, X Zhang, L Zeng, B Richine, J D Bowling, S Fukuda, S Goenka, Z Liu, G-S Feng, M Yu, G E Sandusky, H S Boswell, Z-Y Zhang, R Kapur, R J Chan

Institutions: Indiana University School of Medicine, Indiana University Indianapolis, Shimane University, University of California San Diego, University of Wisconsin–Madison

Language: English

Topic: Protein Tyrosine Phosphatases

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: Riley Children's Foundation, National Institutes of Health, National Institute on Aging, National Heart, Lung, and Blood Institute, National Cancer Institute

Awards: Novel Mechanisms of C-Kit Regulation in Mast Cells, G1770019406, Small Molecule Inhibitors for the Oncogenic Protein Tyrosine Phosphatase SHP2, Improved Therapies for AML in the Elderly, Mechanisms of adhesion and growth control in stem cells, Role of Shp2 in FLT3-ITD induced leukemogenesis, Targeting PRL Phosphatases for Cancer Therapy, Structure/Function of Protein Tyrosine Phosphatases, Indiana University Melvin and Bren Simon Comprehensive Cancer Center Support Grant

OpenAlex ID: W2083085505

FWCI: 1.668

Cites: 64

Cited by: 56

Related to: 10