Year: 2012
Type: article
Study design: Observational Study
Abstract: Using resting-state functional magnetic resonance imaging data from two independent samples of healthy adults, we parsed the amygdala's intrinsic connectivity into three partially distinct large-scale networks that strongly resemble the known anatomical organization of amygdala connectivity in rodents and monkeys. Moreover, in a third independent sample, we discovered that people who fostered and maintained larger and more complex social networks not only had larger amygdala volumes, but also amygdalae with stronger intrinsic connectivity within two of these networks: one putatively subserving perceptual abilities and one subserving affiliative behaviors. Our findings were anatomically specific to amygdalar circuitry in that individual differences in social network size and complexity could not be explained by the strength of intrinsic connectivity between nodes within two networks that do not typically involve the amygdala (i.e., the mentalizing and mirror networks), and were behaviorally specific in that amygdala connectivity did not correlate with other self-report measures of sociality.
Source: Journal of Neuroscience
Language: English
Subfield: Cognitive Neuroscience
Field: Neuroscience
Domain: Life Sciences
Open Access status: hybrid
Awards: Social cognitive impairment in frontotemporal degeneration and schizophrenia, Neural Mechanisms of Affective Salience in Aging, Massachusetts Alzheimer's Disease Research Center, Medial temporal lobe subregions in aging, MCI and AD:Structural and functional M, Emotions are emergent events constrained by affective and conceptual processes.
OpenAlex ID: W2083254659