Work

CHICK CARTILAGE COLLAGEN: A NEW TYPE OF α1 CHAIN NOT PRESENT IN BONE OR SKIN OF THE SPECIES

Year: 1969

Type: article

Abstract: Isolation and chromatography of collagen from chick cartilage revealed an excess of alpha1 relative to alpha2-chains. Characterization of the cyanogen bromide peptides from the alpha1 fraction indicated the presence of two homologous forms of alpha1. The results suggest that cartilage contains two collagens, one identical to the collagen of skin and bone, the other clearly different requiring the expression of an additional structural gene and possibly containing only alpha1-chains.

Source: Proceedings of the National Academy of Sciences

DOI: 10.1073/pnas.64.4.1264

Authors: Edward J. Miller, Victor J. Matukas

Institutions: National Institutes of Health, National Institute of Dental and Craniofacial Research

Language: English

Topic: Collagen: Extraction and Characterization

Subfield: Biomaterials

Field: Materials Science

Domain: Physical Sciences

Open Access status: green

OpenAlex ID: W2083318392

FWCI: 7.976

Cites: 11

Cited by: 335

Related to: 10