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An Update of Cancer Incidence in the Agricultural Health Study

Year: 2010
Type: article
Study design: Observational Study
Abstract: OBJECTIVE: Our objective is to reevaluate cancer incidence among Agricultural Health Study participants. METHODS: Standardized incidence ratios (SIRs) and relative standardized ratios were calculated. RESULTS: A significant excess of prostate cancer was seen for private and commercial applicators (SIR = 1.19, 95% CI 1.14, 1.25 and SIR = 1.28, 95% CI = 1.00, 1.61, respectively). Excesses were observed for lip cancer (SIR = 1.97, 95% CI = 1.02, 3.44) and multiple myeloma (SIR = 1.42, 95% CI = 1.00, 1.95) among private applicators from North Carolina and for marginal zone lymphoma among Iowa spouses (SIR = 2.34, 95% CI = 1.21, 4.09). CONCLUSIONS: Although lower rates of smoking and increased physical activity probably contribute to the lower overall cancer incidence, agricultural exposures including pesticides, viruses, bacteria, sunlight, and other chemicals may increase risks for specific cancer sites.
DOI: 10.1097/jom.0b013e3181f72b7c
Authors: Stella Koutros, Michael C.R. Alavanja, Jay H. Lubin, Dale P. Sandler, Jane A. Hoppin, Charles F. Lynch, Charles Knott, Aaron Blair, Laura E. Beane Freeman
Institutions: University of Iowa, United States Department of Health and Human Services, National Institutes of Health, National Institute of Environmental Health Sciences, National Cancer Institute, Division of Cancer Epidemiology and Genetics, Battelle
Language: English
Subfield: Plant Science
Open Access status: green
OpenAlex ID: W2083514150
FWCI: 13.83
Cites: 73
Cited by: 161
Related to: 10