Work

Crystallization and Preliminary Structural Analysis of Dihydrolipoyl Transsuccinylase, the Core of the 2-Oxoglutarate Dehydrogenase Complex

Year: 1971

Type: article

Abstract: Dihydrolipoyl transsuccinylase, one of the three enzymes comprising the Escherichia coli 2-oxoglutarate dehydrogenase (EC 1.2.4.2) complex, has been crystallized. Studies by x-ray diffraction and electron microscopy establish that the transsuccinylase has octahedral (432) symmetry, i.e., it consists of 24 subunits that are structurally identical.

Source: Proceedings of the National Academy of Sciences

DOI: 10.1073/pnas.68.6.1135

Authors: David J. Derosier, Robert M. Oliver, Lester J. Reed

Institution: The University of Texas at Austin

Language: English

Topic: Biochemical Acid Research Studies

Subfield: Biochemistry

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funders: National Science Foundation, U.S. Public Health Service

OpenAlex ID: W2083729739

FWCI: 1.364

Cites: 5

Cited by: 66

Related to: 10