Work

Mapuche Herbal Medicine Inhibits Blood Platelet Aggregation

Year: 2011

Type: article

Abstract: 12 plant species traditionally used by the Mapuche people in Chile to treat wounds and inflammations have been evaluated for their direct blood platelet inhibition. Seven of the 12 tested plant species showed platelet inhibitory effect in sheep blood, and four of these were also able to inhibit the ADP- (5.0 μM) and collagen- (2.0 μg/mL) induced aggregations in human blood. These four species in respective extracts (in brackets) were Blechnum chilense (MeOH), Luma apiculata (H(2)O), Amomyrtus luma (DCM : MeOH 1 : 1) and Cestrum parqui (DCM : MeOH 1 : 1). The platelet aggregating inhibitory effects of A. luma (DCM : MeOH 1 : 1), and L. apiculata (H(2)O) were substantial and confirmed by inhibition of platelet surface activation markers.

Source: Evidence-based Complementary and Alternative Medicine

DOI: 10.1155/2012/647620

Authors: Susan Skanderup Falkenberg, Inge Tarnow, Alfonso Guzman, Per Mølgaard, Henrik Toft Simonsen

Institutions: University of Copenhagen, Chr. Hansen (Denmark)

Language: English

Topic: Ethnobotanical and Medicinal Plants Studies

Subfield: Plant Science

Field: Agricultural and Biological Sciences

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $2,550