Year: 2003
Type: article
Study design: Observational Study
Abstract: OBJECTIVE: To examine the incidence, correlates, course and family history of bipolar disorder (BD) and subthreshold BD in adolescents. METHOD: Structured diagnostic interviews were conducted with a large community sample of adolescents and their first-degree relatives, and the adolescents were re-evaluated as young adults. RESULTS: The first lifetime onset of BD and subthreshold BD almost always occurred in adolescence. Adolescent BD and subthreshold BD were associated with elevated impairment, comorbidity, and suicide attempts. Adolescents with BD were at increased risk for BD, and adolescents with subthreshold BD were at increased risk for major depressive disorder (MDD) in young adulthood. Relatives of BD adolescents had elevated rates of subthreshold BD and MDD, and relatives of subthreshold BD adolescents had elevated rates of BD and MDD. CONCLUSION: 'Classical' BD clearly exists in adolescence, but there is also a spectrum of milder bipolar conditions. Remediating and preventing BD in adolescents should be a high public health priority.
Source: Acta Psychiatrica Scandinavica
Authors: P. M. Lewinsohn, J. R. Seeley, D. N. Klein
Institutions: Oregon Research Institute, Stony Brook University
Language: English
Subfield: Psychiatry and Mental health
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
Awards: G3453915188, G3904782757, G880177878
OpenAlex ID: W2083915645