Work

Substantial Energetic Improvement with Minimal Structural Perturbation in a High Affinity Mutant Antibody

Year: 2004

Type: article

Source: Journal of Molecular Biology

DOI: 10.1016/j.jmb.2004.08.019

Authors: K.S. Midelfort, H.H. Hernandez, S.M. Lippow, B. Tidor, C.L. Drennan, K.D. Wittrup

Institution: Massachusetts Institute of Technology

Language: English

Topic: Monoclonal and Polyclonal Antibodies Research

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

Open Access status: closed

Funders: National Cancer Institute, National Institute of General Medical Sciences

Awards: G194228926, Interdepartmental Biotechnology Training Program, Engineered Antibody EGFR Antagonist Cancer Therapeutics

OpenAlex ID: W2083997681

FWCI: 6.914

Cites: 57

Cited by: 128

Related to: 10