(+)-epi-α-Bisbolol Is the Wound-Healing Principle of Peperomia galioides: Investigation of the in Vivo Wound-Healing Activity of Related Terpenoids
Year: 2001
Type: article
Abstract: Bioassay-guided investigation of the ethanol extract of Peperomia galioides using a tensile strength method in mice as a monitor led to the isolation of epi-alpha-bisabolol (1) (ED(50) 155 microg/mL). An in vivo healing study of selected commercially available monoterpenoids yielded two bioactive compounds, alpha-bisabolol (2) and alpha-terpineol (3) (ED(50) of 228 and 240 microg/g mouse[corrected], respectively).
Source: Journal of Natural Products
DOI: 10.1021/np0102859
Authors: León F. Villegas, Ana Marçalo, Jennifer Martin, Irma D. Fernández, Holger Maldonado, Abraham J. Vaisberg, Gerald B. Hammond
Language: English
Subfield: Pharmacology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W2084622458