Year: 2013
Type: article
Abstract: The development of noninvasive imaging techniques using monoclonal antibodies (mAbs) is a quickly evolving field. Immuno-PET uses positron-emitting isotopes to track the localization of mAbs with excellent image quality. Procedures for labeling mAbs with (89)Zr or (124)I using good manufacturing procedures have been established, and therefore these radiopharmaceuticals are being investigated for clinical use. This short review will focus on immuno-PET with full mAbs using long-lived positron-emitting isotopes ((89)Zr and (124)I) over the past 5 y and discuss their progress into clinical use.
Source: Journal of Nuclear Medicine
Authors: Brian D. Wright, Suzanne E. Lapi
Institution: Washington University in St. Louis
Language: English
Subfield: Radiology, Nuclear Medicine and Imaging
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W2084688386