Work

Genome Sequences of Mycoplasma alligatoris A21JP2 T and Mycoplasma crocodyli MP145 T

Year: 2011

Type: article

Abstract: Mycoplasma alligatoris and Mycoplasma crocodyli are closely related siblings, one being highly virulent and the other relatively attenuated. We compared their genomes to better understand the mechanisms and origins of M. alligatoris' remarkable virulence amid a clade of harmless or much less virulent species. Although its chromosome was refractory to closure, M. alligatoris differed most notably by its complement of sialidases and other genes of the N-acetylneuraminate scavenging and catabolism pathway.

Source: Journal of Bacteriology

DOI: 10.1128/jb.00309-11

Authors: D. R. Brown, W. G. Farmerie, M. May, G. A. Benders, A. S. Durkin, K. Hlavinka, J. Hostetler, J. Jackson, J. Johnson, R. H. Miller, V. Paralanov, D. Radune, B. Szczypinski, J. I. Glass

Institutions: University of Florida, Towson University, J. Craig Venter Institute

Language: English

Topic: Microbial infections and disease research

Subfield: Microbiology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Human Genome Research Institute, National Institute of General Medical Sciences, National Institute of Allergy and Infectious Diseases

Awards: Linked Virulence and Fitness of Mycoplasma alligatoris, Mycoplasma Model of Infection-mediated Sterile Inflammation, Annotation of the Mycoplasma alligatoris genome

OpenAlex ID: W2085318198

FWCI: 2.061

Cites: 6

Cited by: 17

Related to: 10