Mapping the human brain at rest with diffuse optical tomography
Year: 2009
Type: conference-paper
Abstract: Diffuse optical tomography (DOT) is a portable functional neuroimaging technique that is able to simultaneously measure both oxy- and deoxyhemoglobin responses to brain activity. Herein, we demonstrate a technique for mapping functional connections in the brain by measuring the spatial distribution of temporal correlations in resting brain activity. Simultaneous DOT imaging over the motor and visual cortices yielded robust correlation maps reproducing the expected functional neural architecture. These functional connectivity methods will have utility in certain populations, such as those who are unconscious or very young, who have difficulty performing the behaviors required in traditional task-based functional neuroimaging paradigms.
Institution: Washington University in St. Louis
Language: English
Subfield: Radiology, Nuclear Medicine and Imaging
Field: Medicine
Domain: Health Sciences
Open Access status: green
Awards: The Study of Task-Level Control Signals Using fMRI, G1395292227, Development of Orthographic Knowledge: fMRI Studies, G4537676473, OPTICAL IMAGING OF BRAIN FUNCTION IN THE PRETERM INFANT, 21st-Century Imaging Sciences: Undergraduate and Graduate Student Training, G6978808659, Full Head, High Density Functional Diffuse Optical Tomography, Brain and its Vasculature, G880311769, G949556707
OpenAlex ID: W2085340885