Year: 2007
Type: article
Abstract: Treatment with Convalescent Plasma for Influenza A (H5N1) InfectionTo the Editor: A previously healthy 31-year-old male van driver presented to a local clinic in Shenzhen, in southern China, on June 7, 2006, with a 4-day history of a high fever (temperature, 39.9°C), chills, and a cough with clear sputum.A chest radiograph obtained on June 9 revealed large opacities in the lower lobe of the left lung.A reversetranscriptase-polymerase-chain-reaction (RT-PCR) assay and an isolate from a tracheal aspirate were positive for influenza A (H5N1) virus.Treatment with 150 mg of oseltamivir twice daily was started at 2 a.m. on June 12 (Fig. 1).After 2 days, there was increased consolidation in the right lung and only slight improvement in the left lung.Quantitative RT-PCR revealed a high viral load (1.31×10 5 copies per milliliter) when it was first measured (at 4 a.m.
Source: New England Journal of Medicine
DOI: 10.1056/nejmc070359
Authors: Boping Zhou, Nanshan Zhong, Yi Guan
Language: English
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W2085978024