Work

VSV infection is sensed by Drosophila, attenuates nutrient signaling, and thereby activates antiviral autophagy

Year: 2009

Type: editorial

Abstract: Innate immune mechanisms are the first line of defense against pathogens including viruses. This work identifies autophagy, an innate intracellular degradative pathway, as antiviral against Vesicular Stomatitis Virus (VSV) in Drosophila. VSV is sensed by cells via the surface glycoprotein leading to the attenuation of the nutrient signaling pathway thereby activating an antiviral autophagic program.

Source: Autophagy

DOI: 10.4161/auto.5.7.9730

Author: Sara Cherry

Institution: University of Pennsylvania

Language: English

Topic: Autophagy in Disease and Therapy

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W2086006558

Cites:

Cited by: 24

Related to: 10