Work

Force Generation by Microtubule Assembly/Disassembly in Mitosis and Related Movements

Year: 1995

Type: article

Abstract: In this article, we review the dynamic nature of the filaments (microtubules) that make up the labile fibers of the mitotic spindle and asters, we discuss the roles that assembly and disassembly of microtubules play in mitosis, and we consider how such assembling and disassembling polymer filaments can generate forces that are utilized by the living cell in mitosis and related movements.

Source: Molecular Biology of the Cell

DOI: 10.1091/mbc.6.12.1619

Authors: Shinya Inoué, Edward D. Salmon

Institutions: Marine Biological Laboratory, University of North Carolina at Chapel Hill

Language: English

Topic: Microtubule and mitosis dynamics

Subfield: Cell Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funders: National Institutes of Health, National Institute of General Medical Sciences

Awards: G4221464802, G4397117754, G9000014305