Work

Radiopharmaceuticals in sentinel lymph-node detection – an overview

Year: 1999

Type: article

Abstract: Biopsy of the first tumour-draining lymph node (sentinel node, SN) is bound to become the procedure of choice in regional staging of melanoma and breast cancer patients. Several radiopharmaceuticals have been developed for lymphoscintigraphy. In this paper we review the most frequently used radiopharmaceuticals for their appropriateness in the sentinel-node procedure. We conclude that accurate localization of SNs is demonstrated using technetium-99m-sulfur colloid (99mTc-SC), 99mTc antimony trisulfide colloid (99mTc-ATC) [10] and 99mTc nanocolloidal albumin (99mTc-CA). 99mTc-Ca and 99mTc-SC are both available in Europe. In the United States 99mTc-SC is the only registered tracer for lymphoscintigraphy.

Source: European Journal of Nuclear Medicine

DOI: 10.1007/pl00014793

Authors: Abraham J. Wilhelm, G. Sophie Mijnhout, Eric J. F. Franssen

Institutions: Vrije Universiteit Amsterdam, Amsterdam UMC Location Vrije Universiteit Amsterdam

Language: English

Topic: Radiopharmaceutical Chemistry and Applications

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W2086973839

FWCI: 13.37

Cites: 32

Cited by: 239

Related to: 10