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Cancer-Associated Retinopathy in Neuroendocrine Carcinoma of the Fallopian Tube

Year: 2010

Type: article

Abstract: A 70-year-old woman developed progressive visual loss with compromised visual acuity and visual fields, cells in the anterior chamber and vitreous, attenuated retinal arterioles, and macular edema. She had undergone right oophorectomy and partial salpingectomy nearly 50 years earlier. Full-field and multifocal electroretinography showed waveforms of markedly attenuated amplitudes, findings consistent with cancer-associated retinopathy (CAR). Positron emission tomography revealed a nodule in the anterior wall of a right hydrosalpinx. Total laparoscopic hysterectomy yielded a neuroendocrine fallopian tube malignancy. She underwent partial treatment with paclitaxel and carboplatin that was aborted because of the development of herpes zoster infection. At 15 months following diagnosis, her ophthalmic status was stable. This is the first report of CAR in neuroendocrine carcinoma of the fallopian tube.

Source: Journal of Neuro-Ophthalmology

DOI: 10.1097/wno.0b013e3181e22ef0

Authors: Anitha Raghunath, Grazyna Adamus, Diane C Bodurka, Jinsong Liu, Jade S Schiffman

Institutions: The University of Texas MD Anderson Cancer Center, The University of Texas Medical Branch at Galveston, Oregon Health & Science University

Language: English

Topic: Ocular Oncology and Treatments

Subfield: Ophthalmology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Eye Institute