Work

Guiding Stem Cell Differentiation into Oligodendrocytes Using Graphene‐Nanofiber Hybrid Scaffolds

Year: 2014

Type: article

Abstract: Graphene-nanofiber hybrid scaffolds selectively guide the differentiation of neural stem cells into mature oligodendrocytes, which are the myelinating cells of the central nervous system. Moreover, this process is facilitated without introducing differentiation inducers into the culture media, underscoring the potential of a biomaterials-approach for neural tissue engineering.

Source: Advanced Materials

DOI: 10.1002/adma.201400523

Authors: Shreyas Shah, Perry T. Yin, Thiers M. Uehara, Sy‐Tsong Dean Chueng, Letao Yang, Ki‐Bum Lee

Institutions: Rutgers, The State University of New Jersey, Instituto de Física de São Carlos

Language: English

Topic: Electrospun Nanofibers in Biomedical Applications

Subfield: Biomaterials

Field: Materials Science

Domain: Physical Sciences

Open Access status: bronze

Funders: National Institutes of Health, National Institute of Neurological Disorders and Stroke, National Center for Research Resources, National Center for Chronic Disease Prevention and Health Promotion

Awards: G1775750856, Novel magnetic core/shell nanoparticle-based stem cell therapy to direct neural s, Combinatorial approaches for studying multiple cues regulating human pluripotent, A confocal microscope