Work

De novo fatty-acid synthesis and related pathways as molecular targets for cancer therapy

Year: 2009

Type: review

Abstract: Enhanced lipid biosynthesis is a characteristic feature of cancer. Deregulated lipogenesis plays an important role in tumour cell survival. These observations suggest that enzymes in the lipid synthesis pathway would be rational therapeutic targets for cancer. To this end, we review the enzymes in de novo fatty-acid synthesis and related pathways.

Source: British Journal of Cancer

DOI: 10.1038/sj.bjc.6605007

Authors: T Mashima, H Seimiya, T Tsuruo

Institution: Japanese Foundation For Cancer Research

Language: English

Topic: Cancer, Lipids, and Metabolism

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $5,190