Work

Rheological properties of peptide-based hydrogels for biomedical and other applications

Year: 2010

Type: review

Abstract: Peptide-based hydrogels are an important class of biomaterials finding use in food industry and potential use in tissue engineering, drug delivery and microfluidics. A primary experimental method to explore the physical properties of these hydrogels is rheology. A fundamental understanding of peptide hydrogel mechanical properties and underlying molecular mechanisms is crucial for determining whether these biomaterials are potentially suitable for biotechnological uses. In this critical review, we cover the literature containing rheological characterization of the physical properties of peptide and polypeptide-based hydrogels including hydrogel bulk mechanical properties, gelation mechanisms, and the behavior of hydrogels during and after flow (219 references).

Source: Chemical Society Reviews

DOI: 10.1039/b919449p

Authors: Congqi Yan, Darrin J. Pochan

Institutions: Delaware Biotechnology Institute, University of Delaware

Language: English

Topic: Supramolecular Self-Assembly in Materials

Subfield: Biomaterials

Field: Materials Science

Domain: Physical Sciences

Open Access status: green

Funders: National Institutes of Health, National Institute of Standards and Technology, National Center for Research Resources

Award: Molecular Design of Advanced Biomaterials