Work

Susceptibility of Haemophilus influenzae type b to cefaclor and influence of inoculum size

Year: 1982

Type: article

Abstract: Cefaclor appeared to be an effective antibiotic against both beta-lactamase-positive and beta-lactamase-negative strains of Haemophilus influenzae type b when tested with 10(5) colony-forming units per ml. With inocula in excess of 10(6) colony-forming units per ml, these organisms were neither inhibited nor killed at concentrations of 400 micrograms/ml. This inoculum effect was also demonstrated in time-kill curve studies.

Source: Antimicrobial Agents and Chemotherapy

DOI: 10.1128/aac.22.5.923

Authors: R M Levin, P H Azimi, M G Dunphy

Language: English

Topic: Antibiotic Resistance in Bacteria

Subfield: Molecular Medicine

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2089731748

FWCI: 0.935

Cites: 9

Cited by: 10

Related to: 10