Work

Phorbol ester enhances deoxynucleoside incorporation while inhibiting proliferation of K‐562 cells

Year: 1985

Type: article

Abstract: Recently a new technique has been developed to study bromodeoxyuridine incorporation into DNA as a function of the cell cycle phase distribution. We have made the observation that treatment of the hematopoietic cell line K-562 results in a complete and immediate cessation of cell growth, although tritiated thymidine incorporation is markedly elevated for as long as 5 days. We have made use of that newly described technique to study this phenomenon.

Source: Cytometry

DOI: 10.1002/cyto.990060614

Authors: O. R. Colamonici, J. B. Trepel, L. M. Neckers

Institutions: National Institutes of Health, National Cancer Institute

Language: English

Topic: Biochemical and Molecular Research

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W2090059869

FWCI: 1.015

Cites: 26

Cited by: 18

Related to: 10