Year: 2001
Type: editorial
Abstract: Acute organ injury in the brain death, preservation, and implantation process is increasingly recognized as a mechanism of injury that has detrimental short‐ and long‐term consequences in transplantation (1). A mainstay of organ preservation to prevent ischemia is cooling of the organ to between 1 and 4 °C. Cooling slows adenosine triphosphate (ATP)‐consuming metabolic processes and is typically well tolerated, for up to 48 h in kidney. The heart, on the other hand, tolerates cold ischemia poorly, with preservation times of 6 h or less.
Author: Daniel Shoskes
Institution: Cleveland Clinic Florida
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $4,300
OpenAlex ID: W2090898761