Work

Classification of weakly carcinogenic human papillomavirus types: addressing the limits of epidemiology at the borderline

Year: 2009

Type: article

Abstract: Virtually all cases of cervical cancer are caused by persistent infections with a restricted set of human papillomaviruses (HPV). Some HPV types, like HPV16 and HPV18, are clear and powerful carcinogens. However, the categorization of the most weakly carcinogenic HPV types is extremely challenging. The decisions are important for screening test and vaccine development. This article describes for open discussion an approach recently taken by a World Health Organization International Agency for Research on Cancer (IARC) Monographs Working Group to re-assess the carcinogenicity of different HPV types.

Source: Infectious Agents and Cancer

DOI: 10.1186/1750-9378-4-8

Authors: Mark Schiffman, Gary Clifford, Franco M Buonaguro

Institutions: National Institutes of Health, National Cancer Institute, Division of Cancer Epidemiology and Genetics, Centre international de recherche sur le cancer, Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale"

Language: English

Topic: Cervical Cancer and HPV Research

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,190