Work

Using Variations of Somatosensory Evoked Potentials to Quantify Spinal Cord Injury Level

Year: 2013

Type: article

Abstract: Existing work indicates that the degree of variation of somatosensory evoked potential (SEP) signals between a healthy spinal pathway and spinal pathway affected by spinal cord injury (SCI) can be used to evaluate the integrity of the spinal pathway. This paper develops a metric that exploits the time-domain features of SEP signals (relative amplitude, time scaling, and time duration) in order to quantify the level of SCI. The proposed method is tested on actual SEP signals collected from rodents afflicted with focal demyelination SCI. Results indicate that the proposed method provides a robust assessment of the different degrees of demyelination in the spinal cord.

Source: Engineering

DOI: 10.4236/eng.2013.510b020

Authors: Hasan Mir, Hasan Al-Nashash, Douglas Kerr, Angelo All, Nitish Thakor

Institutions: American University of Sharjah, Johns Hopkins University, Johns Hopkins Medicine

Language: English

Topic: Spinal Cord Injury Research

Subfield: Pathology and Forensic Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

Funder: Maryland Stem Cell Research Fund