Work

A correction to the exact test based on the Ewens sampling distribution

Year: 1996

Type: erratum

Abstract: The exact test for neutrality based on the Ewens sampling distribution described previously (Slatkin, 1994) is not correct. The problem is that the test as described is based on the probability of the ordered configuration of numbers of alleles, while it should be based on the probability of the unordered configuration. The correctly implemented exact test leads to results that are similar to those from the homozygosity test proposed by Watterson (1977) for relatively small sample sizes but can still differ substantially for larger sample sizes. Programs to perform the exact test are available from the author.

Source: Genetics Research

DOI: 10.1017/s0016672300034236

Author: Montgomery Slatkin

Institution: University of California, Berkeley

Language: English

Topic: Genetic diversity and population structure

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: bronze

Funders: National Institutes of Health, National Institute of General Medical Sciences

Award: Analysis of Admixture and Range Expansion in Humans and Extinct Hominims