Variation of Intestinal Activity With Age: a Review.
Year: 1964
Type: article
Abstract: From the day of birth to the time of death, nearly all of the body's nutritional requirements are met by absorption from the intestinal lumen. However, the morphology and function of this absorbing membrane are not constant; they vary with age. The origin of such changes, and their relationship to all of the events that we associate with biologic aging, is as yet uncertain. Studies in this field are of more than passing interest, for they probably hold clues as to how the alterations can be modified. The present discussion of the variation of intestinal activity with age introduces recent experimental findings from this laboratory, as well as a compilation of literature data. Although a comprehensive picture cannot be drawn, some generalizations begin to emerge which may serve as a baseline for later comparisons. Particular mention is made of the effects on the intestine of modalities which have been shown to alter the aging process (particularly dietary changes and ionizing radiation). Intestinal alterations are conveniently described as a function of the
Source: Europe PMC (PubMed Central)
Author: R P SPENCER
Language: English
Subfield: Gastroenterology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W209219767