Work

39. Evaluation of rAAV-1 vs rAAV-8 Vectors and Their Mode of Delivery in Nonhuman Primate Skeletal Muscle

Year: 2006

Type: article

Abstract: AAV serotype and mode of delivery impact on gene transfer efficiency, immunological outcome, and clinical efficacy. Several groups recently described a drug-free limb perfusion technique in the dog, which allows the transduction of the entire limb using rAAV vectors.

Source: Molecular Therapy

DOI: 10.1016/j.ymthe.2006.08.052

Authors: Alice Toromanoff, Yan Cherel, Jack-Yves Deschamps, Valder R. Arruda, Katherine A. High, Hansell H. Stedman, Mark E. Haskins, Fabienne Rolling, Ignacio Anegon, Philippe Moullier, Caroline Le Guiner

Institutions: Inserm, Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement, University of Pennsylvania, Children's Hospital of Philadelphia

Language: English

Topic: Virus-based gene therapy research

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $4,500

OpenAlex ID: W2092720426

FWCI:

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