Work

Single-Walled Carbon Nanotube-Based Chemiresistive Affinity Biosensors for Small Molecules: Ultrasensitive Glucose Detection

Year: 2010

Type: article

Abstract: We report for the first time single-walled carbon nanotube (SWNT)-based chemiresistive affinity sensors for highly sensitive and selective detection of small and/or weakly charged or uncharged molecules using a displacement format. The detection of glucose, a small, weakly charged molecule, by displacement of plant lectin (concavalin A) bound to a polysaccharide (dextran) immobilized on SWNTs with picomolar sensitivity and selectivity over other sugars and human serum proteins is demonstrated as a proof of concept.

Source: Journal of the American Chemical Society

DOI: 10.1021/ja100503b

Authors: Lakshmi N. Cella, Wilfred Chen, Nosang V. Myung, Ashok Mulchandani

Institution: University of California, Riverside

Language: English

Topic: Electrochemical sensors and biosensors

Subfield: Electrical and Electronic Engineering

Field: Engineering

Domain: Physical Sciences

Open Access status: green

Funder: National Institute of Environmental Health Sciences

Award: Wearable Nanosensor Array for Real-Time Monitoring of Diesel and Gasoline Exhaust