Fractal dimension of the retinal vasculature and risk of stroke: A nested case-control study
Year: 2011
Type: article
Study design: Observational Study
Abstract: Recent studies show associations between retinal vascular changes and small infarcts detected on brain imaging, or clinical stroke.1 Fractal dimension has been used as a global measure of the geometric pattern of the retinal vasculature2,3 potentially representing the complex branching pattern of the microvasculature, including the cerebral microvasculature. We have developed an automatic method to assess spectrum fractal dimension (SFD) of the retinal microvasculature using Fourier-transformed images.4,5
Two previous studies have reported cross-sectional associations between retinal fractal dimension and lacunar stroke.6,7 In this study, we aimed to examine the association between baseline SFD and stroke incidence using a case-control sample nested in the Blue Mountains Eye Study (BMES).
### Methods.
The BMES is a population-based cohort study of an urban population aged 49 years or older (n = 3,654), representing 82.4% of eligible population in a defined area of the Blue Mountains region, Australia.1 Stroke cases were defined among participants with no past history of stroke at baseline (1992–1994) but who developed stroke during the subsequent 5 years (1997–1999), or who died from stroke or stroke-related causes by late 2005. Detailed definitions of stroke events and mortality are shown in …
Source: Neurology
Language: English
Topic: Retinal Imaging and Analysis
Subfield: Radiology, Nuclear Medicine and Imaging
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
Funders: Juvenile Diabetes Research Foundation International, American Health Assistance Foundation, Pfizer, Diabetes Australia Research Trust, Judith Jane Mason and Harold Stannett Williams Memorial Foundation, Jack Brockhoff Foundation, Diabetes Australia, Allergan, National Health and Medical Research Council, Japan Society for the Promotion of Science
Awards: 化学修飾電極を用いる微量金属の選択的濃縮と高感度分析法の確立, キッチの美学的研究(その美意識の構造解明), イギリス新古典主義時代の芸術理論の諸相, Gaining knowledge of gene-environment interplay in age-related eye diseases and moving towards personalised health care practice, The Australian Heart Eye Study (AHES), 新しい電導性材料の開発を目的とした黒鉛繊維層間化合物の合成, Genetics of Retinal Narrowing and Cardiovascular Disease, Risk prediction system of retinal disease based on retinal vascular changes., 上方曽我狂言の研究-享保期を中心に-, Translational Clinical Research in Major Eye Diseases (TCR-Eye), Study of genetic and environmental interplay on the risk of AMD, 川端康成-戦後から自殺までの芸術観上の問題点とその推移, Efficacy of Computer-Assisted Measurements for Retinal Artery and Vein in relation to Risk of Stroke
OpenAlex ID: W2093415677