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Genetic Dissection of the Oncogenic mTOR Pathway Reveals Druggable Addiction to Translational Control via 4EBP-eIF4E

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Year: 2010
Type: article
Source: Cancer Cell
DOI: 10.1016/j.ccr.2010.01.021
Authors: Andrew C. Hsieh, Maria Costa, Ornella Zollo, Cole Davis, Morris E. Feldman, Joseph R. Testa, Oded Meyuhas, Kevan M. Shokat, Davide Ruggero
Institutions: University of California, San Francisco, UCSF Helen Diller Family Comprehensive Cancer Center, Howard Hughes Medical Institute, Fox Chase Cancer Center, Hebrew University of Jerusalem, Hadassah Medical Center
Language: English

Topic: PI3K/AKT/mTOR signaling in cancer
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: bronze

Funder: National Cancer Institute
Awards: Delineating the Mechanisms Responsible for Synthetic Lethality in MYC-induced Tumorigenesis Driven by Control of Protein Synthesis, Basis for Lymphomagenesis in Akt2 Transgenic Mice
OpenAlex ID: W2093431913
FWCI: 16.04
Cites: 49
Cited by: 464
Related to: 10
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