Cloning and sequence analysis of cDNA encoding the precursor of a human endothelium‐derived vasoconstrictor peptide, endothelin: Identity of human and porcine endothelin
Year: 1988
Type: article
Abstract: A cDNA encoding a human endothelium-derived vasoconstrictor peptide, endothelin, was isolated from a human placenta cDNA library. The nucleotide sequence of this cDNA clone showed that the primary structure of the human preproendothelin has 212 amino acid residues and is highly homologous to porcine preproendothelin, and that human endothelin is identical with porcine endothelin.
Source: FEBS Letters
Authors: Yasuaki Itoh, Masashi Yanagisawa, Shoichi Ohkubo, Chiharu Kimura, Takuo Kosaka, Akihiro Inoue, Norio Ishida, Youji Mitsui, Haruo Onda, Masahiko Fujino, Tomoh Masaki
Institutions: Takeda (Japan), University of Tsukuba
Language: English
Subfield: Physiology (medical)
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W2093996647