Work

Combination of a novel HDAC inhibitor OBP-801/YM753 and a PI3K inhibitor LY294002 synergistically induces apoptosis in human endometrial carcinoma cells due to increase of Bim with accumulation of ROS

Year: 2013

Type: article

Source: Gynecologic Oncology

DOI: 10.1016/j.ygyno.2013.02.008

Authors: Takashi Yoshioka, Shingo Yogosawa, Takeshi Yamada, Jo Kitawaki, Toshiyuki Sakai

Institution: Kyoto Prefectural University of Medicine

Language: English

Topic: Histone Deacetylase Inhibitors Research

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: Ministry of Education, Culture, Sports, Science and Technology, Japan Society for the Promotion of Science

Awards: Basic research for cancer prevention by combinatorial treatment of food constituents based on the signal transduction pathways associated with carcinogenesis, Gene mutations and abnormal gene expression in ovarian cancer arising from endometriosis, Basic research for development of cancer prevention by inhibitory effect of food constituents on the signal transduction pathways associated with carcinogenesis

OpenAlex ID: W2094066045

FWCI: 1.939

Cites: 46

Cited by: 44

Related to: 10