Work

A Novel Action of Insulin on Phosphoprotein Formation by Mammary Gland Explants

Year: 1969

Type: article

Abstract: Studies on the induction of casein synthesis in competent daughter cells formed in mammary gland explants have revealed a new action of insulin. Treatment with prolactin, in the absence of insulin, is responsible for the formation of some polypeptides which are destined to become phosphoproteins, or for the formation of a unique protein-kinase, or both. In any case, insulin is required for participation of the prolactin-induced factor(s) in a protein-kinase reaction.

Source: Proceedings of the National Academy of Sciences

DOI: 10.1073/pnas.63.1.213

Authors: Anthony E. Voytovich, Ida S. Owens, Yale J. Topper

Institution: National Institutes of Health

Language: English

Topic: Growth Hormone and Insulin-like Growth Factors

Subfield: Endocrinology, Diabetes and Metabolism

Field: Medicine

Domain: Health Sciences

Open Access status: green

OpenAlex ID: W2094187023

FWCI: 4.769

Cites: 7

Cited by: 14

Related to: 10