Three-dimensional preoperative maps of hippocampal atrophy predict surgical outcomes in temporal lobe epilepsy
Year: 2005
Type: article
Study design: Observational Study
Abstract: The authors used surface-based anatomic mapping to detect features of hippocampal anatomy that correlated with surgical outcomes in patients undergoing surgery for mesial temporal lobe epilepsy with hippocampal sclerosis. Compared with a seizure-free group, hippocampal profiles for the non-seizure-free group had greater diffuse ipsilateral atrophy and more region-specific contralateral atrophy in the anterior, lateral hippocampus. These atrophic regions may indicate areas of increased epileptogenicity, contributing to poorer surgical outcomes.
Source: Neurology
Authors: J. J. Lin, N. Salamon, R. A. Dutton, A. D. Lee, J. A. Geaga, K. M. Hayashi, A. W. Toga, J. Engel, P. M. Thompson
Institution: University of California, Los Angeles
Language: English
Subfield: Psychiatry and Mental health
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2094479815