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An Autophagy-Enhancing Drug Promotes Degradation of Mutant α 1 -Antitrypsin Z and Reduces Hepatic Fibrosis

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Year: 2010
Type: article
Source: Science
DOI: 10.1126/science.1190354
Authors: Tunda Hidvegi, Michael Ewing, Pamela Hale, Christine Dippold, Caroline Beckett, Carolyn Kemp, Nicholas Maurice, Amitava Mukherjee, Christina Goldbach, Simon Watkins, George Michalopoulos, David H. Perlmutter
Institution: University of Pittsburgh
Language: English

Topic: Autophagy in Disease and Therapy
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: National Heart, Lung, and Blood Institute, National Institute of Diabetes and Digestive and Kidney Diseases, National Center for Research Resources
Awards: G1614542448, G527901683, Hepatocellular Carcinoma in Antitrypsin Deficiency, Fluorescent Biosensors for Networks and Pathways, Local Expression of Alpha-1-Antitrypsin in Emphysema, G7649582245, Novel Pharmacological Strategies for Liver Disease in Antitrypsin Deficiency
OpenAlex ID: W2094898345
FWCI: 37.94
Cites: 15
Cited by: 604
Related to: 10
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