Sex differences in fitness and selection for centric fusions between sex-chromosomes and autosomes
Year: 1980
Type: article
Abstract: SUMMARY A model of centric fusions between theXorYchromosome and an autosome carrying a selected locus is studied. It is assumed that fusions are not associated with any fitness effects, and that all chromosomes disjoin regularly from their homologues. It is shown that a necessary condition for the fusion to be favoured is that there is a selectively maintained sex difference in allele frequencies at the selected locus. If this condition is satisfied, the initial rate of increase of a rareY-autosome fusion is about three times that of anX-autosome fusion, with the same parameter values. Computer calculations of the final equilibrium states reached by populations containing such fusions were done.
Source: Genetics Research
Authors: D. Charlesworth, B. Charlesworth
Institution: University of Sussex
Language: English
Subfield: Genetics
Domain: Life Sciences
Open Access status: bronze
OpenAlex ID: W2095312765