Year: 2013
Type: article
Abstract: Solubility data were measured for omeprazole sulfide in ethanol, 95 mass-% ethanol, ethyl acetate, isopropanol, methanol, acetone, n -butanol and n -propanol in the temperature range from 280.35 to 319.65 K by employing the gravimetric method. The solubilities increase with temperature and they are in good agreement with the calculated solubility of the modified Apelblat equation and the λh equation. The experimental solubility and correlation equation in this work can be used as essential data and model in the purification process of omeprazole sulfide. The thermodynamic properties of the solution process, including the Gibbs energy, enthalpy, and entropy were calculated using the van’t Hoff equation.
Source: Journal of Solution Chemistry
Authors: Yihua Li, Wenge Yang, Tuan Zhang, Chaoyuan Wang, Kai Wang, Yonghong Hu
Institution: Nanjing Tech University
Language: English
Subfield: Materials Chemistry
Field: Materials Science
Domain: Physical Sciences
Open Access status: hybrid
Estimated APC paid: $3,490
Awards: G6546071524, G6780450436
OpenAlex ID: W2095358722