Work

Screening Toxic Chemicals: How Accurate Must Tests Be?

Year: 1988

Type: article

Abstract: A decision analysis framework is used to explore the value of screening tests for carcinogenicity. Whether a test lowers the social cost of screening depends on the test's sensitivity, specificity, and cost and the social cost of misclassification (exonerating carcinogenic chemicals or condemning noncarcinogenic chemicals). The model shows that the best screening test need not be either the most accurate or the least expensive.

Source: Journal of the American College of Toxicology

DOI: 10.3109/10915818809019533

Authors: L.B. Lave, G.S. Omenn

Institutions: Carnegie Mellon University, University of Washington

Language: English

Topic: Carcinogens and Genotoxicity Assessment

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: bronze

OpenAlex ID: W2095467593

FWCI: 0.701

Cites: 24

Cited by: 8

Related to: 10