Genetic analysis of physiological homeostasis: glomerular filtration rate following saline loading in mice
Year: 1972
Type: article
Abstract: SUMMARY Saline loading caused an increase in glomerular filtration rate in RAP mice but not in CBA mice. On the basis of progeny testing of F 2 hybrids, backcrosses to CBA, and inbred lines derived from backcrosses to RAP, it was concluded that the difference between the strains RAP and CBA was probably largely accounted for by a single gene locus. The use of this gene in physiological investigations of the control of glomerular filtration rate is suggested.
Source: Genetics Research
Authors: J. Stewart, S. Mowbray
Institution: University of Cambridge
Language: English
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W2095594501