High Level of Serum Calcium and Iron Influences the Risk of Type 2 Diabetes Mellitus With Periodontitis
Year: 2014
Type: article
Study design: Observational Study
Abstract: The purpose of the study was to evaluate the serum level of calcium (Ca) and iron (Fe) in type 2 diabetes mellitus (T2DM) with periodontitis subjects. A total of 450 subjects participated in the study, who were all distributed equally into three groups as control healthy individuals (group I), T2DM without periodontitis (group II), and T2DM with periodontitis (group III), matched for age, sex, and duration of diabetes. Serum concentrations of glucose, HbA1c, Ca, and Fe were measured using various methods. Student’s t-test, Pearson correlations, and analysis of variance (ANOVA) tests were used for statistical analysis. The serum Ca and Fe level was found to be significantly increased in T2DM with periodontitis (group III) and lowered in T2DM without periodontitis (group II) (P < 0.0001) when compared to control. Patients with T2DM with periodontitis has increased serum Ca level which are mainly released from the alveolar bone loss and increased Fe level further induces more complications in T2DM with periodontitis.
Authors: D.S. Pushparani, S. Nirmala
Institution: SRM Dental College
Language: English
Subfield: Periodontics
Field: Dentistry
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W2095694960