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Communication and Low Mood (CALM): a randomized controlled trial of behavioural therapy for stroke patients with aphasia

Year: 2012

Type: article

Study designs: Randomized Controlled Trial, Clinical Trial

Abstract: OBJECTIVE: The aim was to evaluate behavioural therapy as a treatment for low mood in people with aphasia. DESIGN: A randomized controlled trial comparing behavioural therapy plus usual care with a usual care control. Potential participants with aphasia after stroke were screened for the presence of low mood. Those who met the criteria and gave consent were randomly allocated. SETTING: Participants were recruited from hospital wards, community rehabilitation, speech and language therapy services and stroke groups. SUBJECTS: Of 511 people with aphasia identified, 105 had low mood and were recruited. INTERVENTIONS: Behavioural therapy was offered for up to three months. Outcomes were assessed three and six months after random allocation. MAIN MEASURES: Stroke Aphasic Depression Questionnaire, Visual Analog Mood Scales 'sad' item, and Visual Analogue Self-Esteem Scale. RESULTS: Participants were aged 29 to 94 years (mean 67.0, SD 13.5) and 66 (63%) were men. Regression analysis showed that at three months, when baseline values and communication impairment were controlled for, group allocation was a significant predictor of the Stroke Aphasic Depression Questionnaire (P < 0.05), visual analogue 'sad' (P = 0.03), and Visual Analogue Self-Esteem Scale (P < 0.01). At six months, group alone was a significant predictor of the Stroke Aphasic Depression Questionnaire (P < 0.05), and remained significant when baseline values were controlled for (P = 0.02). Mean Stroke Aphasic Depression Questionnaire 10-item hospital version scores decreased from baseline to six months by six points in the intervention group as compared with an increase of 1.9 points in the control group. CONCLUSIONS: Behavioural therapy seemed to improve the mood of people with aphasia.

Source: Clinical Rehabilitation

DOI: 10.1177/0269215512462227

Authors: Shirley A Thomas, Marion F Walker, Jamie A Macniven, Helen Haworth, Nadina B Lincoln

Institutions: University of Nottingham, Nottingham University Hospitals NHS Trust, Nottinghamshire Healthcare NHS Foundation Trust

Language: English

Topic: Stroke Rehabilitation and Recovery

Subfield: Rehabilitation

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $4,400