Year: 2007
Type: editorial
Abstract: Despite a dramatic reduction in postmenopausal hormone use after the initial publication of the Women’s Health Initiative results,1-4 a substantial number of women continue to use some form of hormonal supplementation predominately to control menopausal symptoms. The conjugated equine estrogen Premarin (Wyeth Pharmaceuticals, Madison, NJ) is the 22nd most fre-quently prescribed brand name drug in the United States with more than 13 million prescriptions issued in 2006.5 Almost 3 million prescriptions were issued in 2006 for Prempo (Wyeth Pharmaceuticals) a combination of an androgenic progestin with conjugated equine estrogen.5 As the preponderance of clinical trial data indicating an increased risk of breast cancer and an unfavor-able global health index has been for conjugated equine estrogens and progestins, interest in more physiologic types of hormone replacement has soared. These so-called bioidentical forms of hor-
Source: Journal of Clinical Oncology
Author: Carol J. Fabian
Institution: University of Kansas Medical Center
Language: English
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W2095869200