Work

The role of antigen in the development of B-cell chronic lymphocytic leukemia

Year: 2013
Type: other
Abstract: These studies strongly suggest that MALT-lymphomas and M-CLL in majority are highly selected for single extrinsic antigens and that these antigens can be both self-antigens and exo-antigens. Our finding that primary CLL cells are responsive to stimulation with their cognate antigen suggests that antigen-dependent BCR signaling may drive CLL expansion in vivo.
Language: English
Subfield: Hematology
Field: Medicine
Open Access status: green
OpenAlex ID: W2096001051
Cites: 111
Cited by:
Related to: 10