Work

Immunoglobulin M Enzyme-Linked Immunosorbent Assay Using Recombinant Polypeptides for Diagnosis of Dengue

Year: 2005

Type: article

Abstract: We demonstrate that a mixture of four recombinant dengue virus E polypeptides corresponding to the N-terminal region of the envelope protein from all serotypes substitutes for standard antigens in two immunoglobulin M enzyme-linked immunosorbent assay formats with 100% concordance, making these polypeptides a useful and accessible reagent for serological diagnosis of dengue in endemic countries.

Source: Clinical and Vaccine Immunology

DOI: 10.1128/cdli.12.7.882-884.2005

Authors: Elsa Videa, Maria Josefina Coloma, Flavia Barreto dos Santos, Angel Balmaseda, Eva Harris

Institutions: Ministerio de Salud, Instituto Oswaldo Cruz, University of California, Berkeley

Language: English

Topic: Mosquito-borne diseases and control

Subfield: Public Health, Environmental and Occupational Health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

Funder: Fogarty International Center