Work

MRI-based prostate brachytherapy seed localization

Year: 2010

Type: conference-paper

Abstract: A magnetic resonance imaging (MRI) pulse sequence and a corresponding image processing algorithm to localize prostate brachytherapy seeds during or after therapy are presented. Inversion-Recovery with ON-resonant water suppression (IRON) is an MRI methodology that generates positive contrast in regions of magnetic field susceptibility, as created by prostate brachytherapy seeds. Phantoms comprising of several materials found in brachytherapy seeds were created to assess the usability of the IRON pulse sequence for imaging seeds. Resulting images show that seed materials are clearly visible with high contrast using IRON, agreeing with theoretical predictions. A seed localization algorithm to process IRON images demonstrates the potential of this imaging technique for seed localization and dosimetry.

Source: IEEE International Symposium on Biomedical Imaging: From Nano to Macro (ISBI)

DOI: 10.1109/isbi.2010.5490259

Authors: Nathanael Kuo, Junghoon Lee, Clare Tempany, Matthias Stuber, Jerry Prince

Institutions: Johns Hopkins University, Brigham and Women's Hospital

Language: English

Topic: Advanced MRI Techniques and Applications

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Cancer Institute