Work

Mazindol treatment for cocaine dependence

Year: 1995

Type: article

Study designs: Randomized Controlled Trial, Clinical Trial

Abstract: This double-blind placebo-controlled treatment study tested the efficacy of mazindol in currently cocaine-dependent out-patients. Forty-three patients were randomized to mazindol (2 mg QD) vs. placebo treatment for 6 weeks. All patients received weekly group counseling. Patients improved with respect to objective (urine toxicology) and subjective (self-report of times used, dollars spent, craving, etc.) measures. There was no response difference between patients treated with mazindol and those who received placebo.

Source: Drug and Alcohol Dependence

DOI: 10.1016/0376-8716(95)01174-4

Authors: Susan M. Stine, John H. Krystal, Thomas R. Kosten, Dennis S. Charney

Institutions: Yale University, VA Connecticut Healthcare System, Connecticut Mental Health Center

Language: English

Topic: Substance Abuse Treatment and Outcomes

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $4,380